Ingredient 6 of 9
Pomegranate Extract in Prostadine: What Is Known About PSA, Blood Flow and Testosterone
Pomegranate extract is the sixth line on the Prostadine info page, with the benefit lines “Maintains healthy blood flow” and “Supports testosterone levels”. Research on pomegranate juice and PSA is conflicting, erection findings are preliminary, and testosterone is not addressed. The extract amount is not printed.
Written by the Prostadine label deskUpdated
What it is01
What pomegranate extract is, and what the info page says about it
Pomegranate (Punica granatum) is a fruit with a deep red juice rich in plant compounds called polyphenols. Extracts are made by concentrating those compounds from the fruit, the peel or the seeds, and products differ a lot in what they contain.
The Prostadine info page lists “Pomegranate Extract” as its sixth line. It does not say which part of the fruit is used or how strong the extract is, and no amount is printed. Two benefit lines go with it: “Maintains healthy blood flow” and “Supports testosterone levels”.
Unlike most of the seaweed lines, pomegranate is an ordinary food that many people drink as juice, so its safety profile is easier to describe. The harder question is whether an unknown amount of extract in a 2 mL serving does anything for the prostate, blood flow or hormones.
| Name on the info page | Pomegranate Extract |
|---|---|
| What it is | Punica granatum fruit |
| Place on the info page | 6 of 9 (not a verified weight order) |
| Amount in Prostadine | Not printed in any image we have |
| Amount used in research | 8 oz of juice a day was used in a long safety follow-up; extract trials differ |
| Strength of evidence | Conflicting results on PSA; preliminary signals on erections |
| Marketed or traditional use | Fruit with polyphenols |
| Main caution | Diarrhea at higher doses; possible interaction with warfarin and statins (case reports). |
| Info-page benefit lines | “Maintains healthy blood flow” / “Supports testosterone levels” |
The research02
Three questions, three different answers
A Memorial Sloan Kettering review summarises what has been found, and it is a mixed picture (MSK, Pomegranate).
On PSA, the data are described as conflicting. Some studies looked at whether pomegranate juice slows the rise of PSA in men whose PSA was already rising after treatment for prostate cancer, and results did not agree. That is a narrow group, and it is not the same as a man with urinary symptoms from an enlarged prostate who takes drops.
On blood flow, preliminary human studies suggest a possible benefit for erectile function. Preliminary means small and early, so the right reading is “worth studying” and not “proven”. On testosterone, the same review does not address it, so the info page's second benefit line has no support in the source we checked.
| Info-page line | What was looked at | What the summary says |
|---|---|---|
| “Maintains healthy blood flow” | Erectile function in preliminary human studies | A possible benefit; early research (MSK, Pomegranate) |
| “Supports testosterone levels” | Testosterone | Not addressed in the review (MSK, Pomegranate) |
| Prostate | PSA rise in men with raised PSA | Conflicting data (MSK, Pomegranate) |
| Safety | Eight ounces of juice a day for over two years | Generally well tolerated (MSK, Pomegranate) |
The amount problem03
Eight ounces of juice is not a drop of extract
The only dose the review mentions is 8 ounces (about 240 mL) of juice a day, used for more than two years in a safety follow-up (MSK, Pomegranate). That is 120 times the whole volume of Prostadine's daily serving, which is 2 mL.
No sensible reading says a few milligrams of extract inside nine ingredients matches a glass of juice a day. Whether the extract is concentrated enough to compensate depends on a number that is not printed. This is the same gap that runs through the whole formula: research on a food or herb at a known dose, set beside a bottle with no printed amounts.
If you like pomegranate, the fruit and the juice are food. Juice carries sugar and calories, so people with diabetes or on calorie limits should count it like any other juice.
Reading an extract line04
Three questions to ask about any “extract” on a label
The word extract covers a wide range of products, so it helps to ask the same three questions of any extract line, whatever the plant.
Which part of the plant?
Fruit, seed, peel and juice powders differ. A label that gives only the plant name leaves this open, as the Prostadine info page does.
How strong is it?
A standardised extract states a marker compound and its percentage, so one batch can be compared with the next and with a trial. Without that, two bottles can differ widely.
How many milligrams per serving?
Only a printed amount lets you compare the product with a studied dose. Here the studied reference is juice, so the comparison is rough even with a number.
None of these questions is a gotcha. They are what a pharmacist would ask before recommending any herbal product, and the answers are what the bottle's panel would normally supply.
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See packsSafety05
Side effects and medicine interactions
Pomegranate is generally well tolerated, with diarrhea reported at higher doses (MSK, Pomegranate). Two interaction notes are worth knowing, even though both rest on limited evidence.
- Warfarin. A case report suggests pomegranate may interact with this blood thinner, so anyone taking warfarin should ask a pharmacist before adding an extract (MSK, Pomegranate).
- Statins. The juice may raise the risk of a muscle problem called rhabdomyolysis in people taking statin cholesterol medicines, so ask your doctor if you take one (MSK, Pomegranate).
- Stopping medicine. Never change a prescription because of a supplement. If an interaction worries you, ask your doctor or pharmacist what to do.
Because Prostadine combines nine lines, the iodine from the seaweeds and the possible bleeding effect of saw palmetto matter more than pomegranate for most readers. See the side effects page for the combined picture.
Verdict06
What the evidence supports
What is in its favour
- A familiar food with a good safety record in a two-year follow-up (MSK, Pomegranate)
- Plausible early signals on erections, worth further study (MSK, Pomegranate)
What counts against it
- Conflicting data on PSA (MSK, Pomegranate)
- No support found for the testosterone line
- Amount and extract type not printed
Pomegranate is a reasonable food. As a line on a prostate label it is a hopeful ingredient with mixed evidence and an unknown amount. Compare it with the stronger-tested herb on the saw palmetto page, or move to the next line on the ingredients page.
- Pomegranate. Memorial Sloan Kettering Cancer Center, Integrative Medicine, 2022.Data are conflicting on whether pomegranate juice slows PSA rise in men with raised PSA. Preliminary human studies suggest a possible benefit for erectile function. Testosterone is not addressed. The only dose cited is 8 ounces of juice a day, used for over 2 years in a safety observation. Generally well tolerated; diarrhea at higher doses. A case report suggests interaction with warfarin; juice may raise rhabdomyolysis risk with statins.
FAQ07
Prostadine questions people ask
Does pomegranate help the prostate?
Evidence is mixed. A summary from Memorial Sloan Kettering says data are conflicting on whether pomegranate juice slows PSA rise in men with raised PSA (MSK, Pomegranate). No trial tested a pomegranate extract inside Prostadine.
Does pomegranate raise testosterone?
The review we checked does not address testosterone (MSK, Pomegranate). The info page claims it “Supports testosterone levels”, and we found no trial that supports that line.
Can I take pomegranate with warfarin or a statin?
Ask your doctor or pharmacist. A case report suggests an interaction with warfarin, and the juice may raise muscle-injury risk with statins (MSK, Pomegranate).
How much pomegranate is in Prostadine?
No amount is printed in any image or page we have. The only research dose cited is 8 ounces of juice a day, which is far more liquid than the 2 mL daily serving.
Who wrote this08
Written and reviewed by
Pages built from the bottle photos, the info page and linked NIH, FDA, NCI, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a licensed U.S. retail desk for Prostadine, not by the manufacturer. We earn money when you buy through our order links.
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